| Physico-Chimie Curie |  |
Journal articles
Modeling the effects of lipid peroxidation during ferroptosis on membrane properties
Abstract : Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid hydroperoxides. There has been significant research on the pathways leading to the accumulation of oxidized lipids, but the downstream effects and how lipid peroxides cause cell death during ferroptosis remain a major puzzle. We evaluated key features of ferroptosis in newly developed molecular dynamics models of lipid membranes to investigate the biophysical consequences of lipid peroxidation, and generated hypotheses about how lipid peroxides contribute to cell death during ferroptosis.
https://hal.archives-ouvertes.fr/hal-03366986
Contributor : Patricia Bassereau Connect in order to contact the contributor
Submitted on : Wednesday, October 6, 2021 - 5:38:23 AM
Last modification on : Tuesday, January 4, 2022 - 4:58:36 AM
Long-term archiving on: : Friday, January 7, 2022 - 6:10:38 PM
Contributor : Patricia Bassereau Connect in order to contact the contributor
Submitted on : Wednesday, October 6, 2021 - 5:38:23 AM
Last modification on : Tuesday, January 4, 2022 - 4:58:36 AM
Long-term archiving on: : Friday, January 7, 2022 - 6:10:38 PM
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Sci-Rep-Ferroptosis.pdf
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