Eukaryotic and archaeal translation initiation factor 2: a heterotrimeric tRNA carrier. - Archive ouverte HAL Access content directly
Journal Articles FEBS Letters Year : 2010

Eukaryotic and archaeal translation initiation factor 2: a heterotrimeric tRNA carrier.

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Abstract

Eukaryotic/archaeal translation initiation factor 2 (e/aIF2) is a heterotrimeric GTPase that plays a key role in selection of the correct start codon on messenger RNA. This review integrates structural and functional data to discuss the involvement of the three subunits in initiator tRNA binding. A possible role of the peripheral subunits in modulating the guanine nucleotide cycle on the core subunit is also addressed.
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hal-00498253 , version 1 (07-07-2010)

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Emmanuelle Schmitt, Marie Naveau, Yves Mechulam. Eukaryotic and archaeal translation initiation factor 2: a heterotrimeric tRNA carrier.. FEBS Letters, 2010, 584 (2), pp.405-12. ⟨10.1016/j.febslet.2009.11.002⟩. ⟨hal-00498253⟩
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