C. Ainsworth, Cilia: Tails of the unexpected, Nature, vol.293, issue.7154, pp.638-641, 2007.
DOI : 10.1038/448638a

H. Dawe, H. Farr, and K. Gull, Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells, Journal of Cell Science, vol.120, issue.1, pp.7-15, 2007.
DOI : 10.1242/jcs.03305

E. Nigg and J. Raff, Centrioles, Centrosomes, and Cilia in Health and Disease, Cell, vol.139, issue.4, pp.663-678, 2009.
DOI : 10.1016/j.cell.2009.10.036

D. Mitchell and M. Nakatsugawa, flagella, The Journal of Cell Biology, vol.68, issue.5, pp.709-715, 2004.
DOI : 10.1242/jcs.01297

D. Wheatley, A. Wang, and G. Strugnell, EXPRESSION OF PRIMARY CILIA IN MAMMALIAN CELLS, Cell Biology International, vol.20, issue.1, pp.73-81, 1996.
DOI : 10.1006/cbir.1996.0011

B. Afzelius, Cilia-related diseases, The Journal of Pathology, vol.55, issue.Suppl 138, pp.470-477, 2004.
DOI : 10.1002/path.1652

M. King, A. Gilboa, F. Meyer, and A. Silberberg, On the transport of mucus and its rheologic simulants in ciliated systems, Am Rev Respir Dis, vol.110, pp.740-745, 1974.

W. Ma, S. Silberberg, and Z. Priel, Distinct Axonemal Processes Underlie Spontaneous and Stimulated Airway Ciliary Activity, The Journal of General Physiology, vol.280, issue.6, pp.875-885, 2002.
DOI : 10.1085/jgp.20028519

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229561

L. Gheber and Z. Priel, Metachronal activity of cultured mucociliary epithelium under normal and stimulated conditions, Cell Motility and the Cytoskeleton, vol.175, issue.4, pp.333-345, 1994.
DOI : 10.1002/cm.970280407

S. Mason, A. Paradiso, and R. Boucher, Regulation of transepithelial ion transport and intracellular calcium by extracellular ATP in human normal and cystic fibrosis airway epithelium, British Journal of Pharmacology, vol.132, issue.Suppl. 10, pp.1649-1656, 1991.
DOI : 10.1111/j.1476-5381.1991.tb09842.x

D. Ovadyahu, D. Eshel, and Z. Priel, Intensification of ciliary motility by extracellular ATP, Biorheology, vol.25, pp.489-501, 1988.

M. Salathe, Regulation of Mammalian Ciliary Beating, Annual Review of Physiology, vol.69, issue.1, pp.401-422, 2007.
DOI : 10.1146/annurev.physiol.69.040705.141253

M. Salathe, E. Lipson, P. Ivonnet, and R. Bookman, Muscarinic signaling in ciliated tracheal epithelial cells: dual effects on Ca2+ and ciliary beating, Am J Physiol, vol.272, pp.301-310, 1997.

M. Sanderson and E. Dirksen, Mechanosensitive and Beta-Adrenergic Control of the Ciliary Beat Frequency of Mammalian Respiratory Tract Cells in Culture, American Review of Respiratory Disease, vol.139, issue.2, pp.432-440, 1989.
DOI : 10.1164/ajrccm/139.2.432

M. Villalon, T. Hinds, and P. Verdugo, Stimulus-response coupling in mammalian ciliated cells. Demonstration of two mechanisms of control for cytosolic [Ca2+], Biophysical Journal, vol.56, issue.6, pp.1255-1258, 1989.
DOI : 10.1016/S0006-3495(89)82772-9

T. Weiss, L. Gheber, V. Shoshan-barmatz, and Z. Priel, Possible mechanism of ciliary stimulation by extracellular ATP: Involvement of calcium-dependent potassium channels and exogenous Ca2+, The Journal of Membrane Biology, vol.127, issue.3, pp.185-193, 1992.
DOI : 10.1007/BF00231506

L. Wong and D. Yeates, Luminal Purinergic Regulatory Mechanisms of Tracheal Ciliary Beat Frequency, American Journal of Respiratory Cell and Molecular Biology, vol.7, issue.4, pp.447-454, 1992.
DOI : 10.1165/ajrcmb/7.4.447

O. Zagoory, A. Braiman, L. Gheber, and Z. Priel, Role of calcium and calmodulin in ciliary stimulation induced by acetylcholine, Am J Physiol Cell Physiol, vol.280, pp.100-109, 2001.

N. Valeyev, D. Bates, Y. Umezawa, A. Gizatullina, and N. Kotov, Systems Biology of Cell Behavior, Methods Mol Biol, vol.662, pp.79-95, 2010.
DOI : 10.1007/978-1-60761-800-3_4

M. Bettencourt-dias and D. Glover, Centrosome biogenesis and function: centrosomics brings new understanding, Nature Reviews Molecular Cell Biology, vol.23, issue.6, pp.451-463, 2007.
DOI : 10.1038/nrm2180

C. Branche, L. Kohl, G. Toutirais, J. Buisson, J. Cosson et al., Conserved and specific functions of axoneme components in trypanosome motility, Journal of Cell Science, vol.119, issue.16, pp.3443-3455, 2006.
DOI : 10.1242/jcs.03078

URL : https://hal.archives-ouvertes.fr/hal-00108209

Z. Carvalho-santos, P. Machado, P. Branco, F. Tavares-cadete, A. Rodrigues-martins et al., Stepwise evolution of the centriole-assembly pathway, Journal of Cell Science, vol.123, issue.9, pp.1414-1426, 2010.
DOI : 10.1242/jcs.064931

F. Hildebrandt and E. Otto, Cilia and centrosomes: a unifying pathogenic concept for cystic kidney disease?, Nature Reviews Genetics, vol.157, issue.12, pp.928-940, 2005.
DOI : 10.1038/nrg1727

B. Piasecki, J. Burghoorn, and P. Swoboda, Regulatory Factor X (RFX)-mediated transcriptional rewiring of ciliary genes in animals, Proceedings of the National Academy of Sciences, vol.107, issue.29, pp.12969-12974, 2010.
DOI : 10.1073/pnas.0914241107

P. Satir and S. Christensen, Structure and function of mammalian cilia, Histochemistry and Cell Biology, vol.13, issue.4, Suppl, pp.687-693, 2008.
DOI : 10.1007/s00418-008-0416-9

R. Eckert, Y. Naitoh, and K. Friedman, Sensory mechanisms in Paramecium. I. Two components of the electric response to mechanical stimulation of the anterior surface, J Exp Biol, vol.56, pp.683-694, 1972.

A. Murakami and R. Eckert, Cilia: Activation Coupled to Mechanical Stimulation by Calcium Influx, Science, vol.175, issue.4028, pp.1375-1377, 1972.
DOI : 10.1126/science.175.4028.1375

Y. Naitoh, R. Eckert, and K. Friedman, A regenerative calcium response in Paramecium, J Exp Biol, vol.56, pp.667-681, 1972.

A. Braiman and Z. Priel, Intracellular stores maintain stable cytosolic Ca2+ gradients in epithelial cells by active Ca2+ redistribution, Cell Calcium, vol.30, issue.6, pp.361-371, 2001.
DOI : 10.1054/ceca.2001.0245

M. Salathe and R. Bookman, action on ciliary beat frequency in single ovine airway epithelial cells, The Journal of Physiology, vol.270, issue.3, pp.851-865, 1999.
DOI : 10.1111/j.1469-7793.1999.00851.x

O. Zagoory, A. Braiman, and Z. Priel, The Mechanism of Ciliary Stimulation by Acetylcholine, The Journal of General Physiology, vol.280, issue.4, pp.329-339, 2002.
DOI : 10.1165/ajrcmb/7.4.447

Z. Dong, P. Saikumar, J. Weinberg, and M. Venkatachalam, CALCIUM IN CELL INJURY AND DEATH, Annual Review of Pathology: Mechanisms of Disease, vol.1, issue.1, pp.405-434, 2006.
DOI : 10.1146/annurev.pathol.1.110304.100218

S. Orrenius, B. Zhivotovsky, and P. Nicotera, Calcium: Regulation of cell death: the calcium???apoptosis link, Nature Reviews Molecular Cell Biology, vol.4, issue.7, pp.552-565, 2003.
DOI : 10.1038/nrm1150

A. Korngreen and Z. Priel, Purinergic stimulation of rabbit ciliated airway epithelia: control by multiple calcium sources., The Journal of Physiology, vol.497, issue.1, pp.53-66, 1996.
DOI : 10.1113/jphysiol.1996.sp021749

A. Braiman, V. Gold-'shtein, and Z. Priel, Feasibility of a Sustained Steep Ca2+Gradient in the Cytosol of Electrically Non-excitable Cells, Journal of Theoretical Biology, vol.206, issue.1, pp.115-130, 2000.
DOI : 10.1006/jtbi.2000.2104

N. Uzlaner and Z. Priel, enhances ciliary activity in rabbit trachea, The Journal of Physiology, vol.270, issue.1, pp.179-190, 1999.
DOI : 10.1111/j.1469-7793.1999.179aa.x

C. Geary, C. Davis, A. Paradiso, and R. Boucher, Role of CNP in human airways: cGMP-mediated stimulation of ciliary beat frequency, Am J Physiol, vol.268, pp.1021-1028, 1995.

A. Schmid, G. Bai, N. Schmid, M. Zaccolo, L. Ostrowski et al., Real-time analysis of cAMP-mediated regulation of ciliary motility in single primary human airway epithelial cells, Journal of Cell Science, vol.119, issue.20, pp.4176-4186, 2006.
DOI : 10.1242/jcs.03181

T. Wyatt, M. Forget, J. Adams, and J. Sisson, Both cAMP and cGMP are required for maximal ciliary beat stimulation in a cell-free model of bovine ciliary axonemes, AJP: Lung Cellular and Molecular Physiology, vol.288, issue.3, pp.546-551, 2005.
DOI : 10.1152/ajplung.00107.2004

B. Yang, R. Schlosser, and T. Mccaffrey, Dual signal transduction mechanisms modulate ciliary beat frequency in upper airway epithelium, Am J Physiol, vol.270, pp.745-751, 1996.

L. Zhang and M. Sanderson, The role of cGMP in the regulation of rabbit airway ciliary beat frequency, The Journal of Physiology, vol.551, issue.3, pp.765-776, 2003.
DOI : 10.1113/jphysiol.2003.041707

T. Hamasaki, K. Barkalow, R. J. Satir, and P. , cAMP-stimulated phosphorylation of an axonemal polypeptide that copurifies with the 22S dynein arm regulates microtubule translocation velocity and swimming speed in Paramecium., Proceedings of the National Academy of Sciences, vol.88, issue.18, pp.7918-7922, 1991.
DOI : 10.1073/pnas.88.18.7918

T. Hamasaki, K. Barkalow, and P. Satir, Regulation of ciliary beat frequency by a dynein light chain, Cell Motility and the Cytoskeleton, vol.27, issue.2, pp.121-124, 1995.
DOI : 10.1002/cm.970320210

P. Satir, K. Barkalow, and T. Hamasaki, Ciliary beat frequency is controlled by a dynein light chain phosphorylation, Biophys J, vol.68, p.222, 1995.

M. Salathe, M. Pratt, and A. Wanner, Cyclic AMP-dependent Phosphorylation of a 26 kD Axonemal Protein in Ovine Cilia Isolated from Small Tissue Pieces, American Journal of Respiratory Cell and Molecular Biology, vol.9, issue.3, pp.306-314, 1993.
DOI : 10.1165/ajrcmb/9.3.306

J. Pernberg and H. Machemer, Voltage-dependence of ciliary activity in the ciliate Didinium nasutum, J Exp Biol, vol.198, pp.2537-2545, 1995.

Y. Nakaoka, T. Imaji, M. Hara, and N. Hashimoto, Spontaneous fluctuation of the resting membrane potential in Paramecium: amplification caused by intracellular Ca2+, Journal of Experimental Biology, vol.212, issue.2, pp.270-276, 2009.
DOI : 10.1242/jeb.023283

P. Brehm and R. Eckert, An electrophysiological study of the regulation of ciliary beating frequency in Paramecium., The Journal of Physiology, vol.283, issue.1, pp.557-568, 1978.
DOI : 10.1113/jphysiol.1978.sp012519

Y. Iwadate and Y. Nakaoka, Calcium regulates independently ciliary beat and cell contraction in Paramecium cells, Cell Calcium, vol.44, issue.2, pp.169-179, 2008.
DOI : 10.1016/j.ceca.2007.11.006

Y. Naitoh, Reversal Response Elicited in Nonbeating Cilia of Paramecium by Membrane Depolarization, Science, vol.154, issue.3749, pp.660-662, 1966.
DOI : 10.1126/science.154.3749.660

Y. Naitoh and R. Eckert, Ionic Mechanisms Controlling Behavioral Responses of Paramecium to Mechanical Stimulation, Science, vol.164, issue.3882, pp.963-965, 1969.
DOI : 10.1126/science.164.3882.963

J. Schultz, Y. Guo, G. Kleefeld, and H. Volkel, Hyperpolarization- and Depolarization-activated Ca 2+ Currents in Paramecium Trigger Behavioral Changes and cGMP Formation Independently, Journal of Membrane Biology, vol.156, issue.3, pp.251-259, 1997.
DOI : 10.1007/s002329900205

K. Oami and M. Takahashi, K + -induced Ca 2+ Conductance Responsible for the Prolonged Backward Swimming in K + -agitated Mutant of Paramecium caudatum, Journal of Membrane Biology, vol.195, issue.2, pp.85-92, 2003.
DOI : 10.1007/s00232-003-2047-3

K. Oami and M. Takahashi, Identification of the Ca2+ Conductance Responsible for K+-induced Backward Swimming in Paramecium caudatum, Journal of Membrane Biology, vol.190, issue.2, pp.159-165, 2002.
DOI : 10.1007/s00232-002-1031-7

L. Gheber and Z. Priel, Synchronization between beating cilia, Biophysical Journal, vol.55, issue.1, pp.183-191, 1989.
DOI : 10.1016/S0006-3495(89)82790-0

URL : http://doi.org/10.1016/s0006-3495(89)82790-0

L. Gheber, A. Korngreen, and Z. Priel, Effect of viscosity on metachrony in mucus propelling cilia, Cell Motility and the Cytoskeleton, vol.75, issue.1, pp.9-20, 1998.
DOI : 10.1002/(SICI)1097-0169(1998)39:1<9::AID-CM2>3.0.CO;2-3

A. Hilfinger and F. Julicher, The chirality of ciliary beats, Physical Biology, vol.5, issue.1, p.16003, 2008.
DOI : 10.1088/1478-3975/5/1/016003

K. Castillo, J. Bacigalupo, and D. Wolff, channels from rat olfactory cilia characterized in planar lipid bilayers, FEBS Letters, vol.188, issue.7, pp.1675-1682, 2005.
DOI : 10.1016/j.febslet.2005.01.079

M. Doughty and S. Dryl, Control of ciliary activity in Paramecium: An analysis of chemosensory transduction in a eukaryotic unicellular organism, Progress in Neurobiology, vol.16, issue.1, pp.1-115, 1981.
DOI : 10.1016/0301-0082(81)90008-3

Y. Iwadate and T. Suzaki, Ciliary reorientation is evoked by a rise in calcium level over the entire cilium, Cell Motility and the Cytoskeleton, vol.4, issue.4, pp.197-206, 2004.
DOI : 10.1002/cm.10165

F. Kawai, Ca2+-Activated K+ Currents Regulate Odor Adaptation by Modulating Spike Encoding of Olfactory Receptor Cells, Biophysical Journal, vol.82, issue.4, pp.2005-2015, 2002.
DOI : 10.1016/S0006-3495(02)75549-5

N. Valeyev, D. Bates, P. Heslop-harrison, I. Postlethwaite, and N. Kotov, Elucidating the mechanisms of cooperative calcium-calmodulin interactions: a structural systems biology approach, BMC Systems Biology, vol.2, issue.1, p.48, 2008.
DOI : 10.1186/1752-0509-2-48

N. Valeyev, P. Heslop-harrison, I. Postlethwaite, N. Kotov, and D. Bates, Multiple calcium binding sites make calmodulin multifunctional, Mol. BioSyst., vol.299, issue.Pt 1, pp.66-73, 2008.
DOI : 10.1039/B713461D

N. Valeyev, P. Heslop-harrison, I. Postlethwaite, A. Gizatullina, N. Kotov et al., Crosstalk between G-protein and Ca2+ pathways switches intracellularcAMP levels, Mol. BioSyst., vol.246, issue.Pt 2, pp.43-51, 2009.
DOI : 10.1039/B807993E

R. Eckert and P. Brehm, Ionic Mechanisms of Excitation in Paramecium, Annual Review of Biophysics and Bioengineering, vol.8, issue.1, pp.353-383, 1979.
DOI : 10.1146/annurev.bb.08.060179.002033

H. Bannai, M. Yoshimura, K. Takahashi, and C. Shingyoji, Calcium regulation of microtubule sliding in reactivated sea urchin sperm flagella, J Cell Sci, vol.113, pp.831-839, 2000.

S. Hayashi and C. Shingyoji, and ADP, Cell Motility and the Cytoskeleton, vol.64, issue.Part 2, pp.292-301, 2009.
DOI : 10.1002/cm.20360

I. Nakano, T. Kobayashi, M. Yoshimura, and C. Shingyoji, Central-pair-linked regulation of microtubule sliding by calcium in flagellar axonemes, Journal of Cell Science, vol.116, issue.8, pp.1627-1636, 2003.
DOI : 10.1242/jcs.00336

S. Tamm, /. Ca, and . Ba, Ca/Ba/Sr-induced conformational changes of ciliary axonemes, Cell Motility and the Cytoskeleton, vol.59, issue.3, pp.187-196, 1990.
DOI : 10.1002/cm.970170306

M. Doughty, Control of ciliary activity in Paramecium???II modification of K+-induced ciliary reversal by cholinergic ligands and quaternary ammonium compounds, Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, vol.61, issue.2, pp.375-384, 1978.
DOI : 10.1016/0306-4492(78)90073-4

M. Doughty, Control of ciliary activity in Paramecium???I modification of K+-induced ciliary reversal by temperature and ruthenium red, Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, vol.61, issue.2, pp.369-373, 1978.
DOI : 10.1016/0306-4492(78)90072-2

Y. Rudy and J. Silva, Computational biology in the study of cardiac ion channels and cell electrophysiology, Quarterly Reviews of Biophysics, vol.39, issue.01, pp.57-116, 2006.
DOI : 10.1017/S0033583506004227

N. Valeyev, A. Downing, A. Skorinkin, I. Campbell, and N. Kotov, A calcium dependent de-adhesion mechanism regulates the direction and rate of cell migration: a mathematical model, In Silico Biol, vol.6, pp.545-572, 2006.

I. Bezprozvanny, J. Watras, and B. Ehrlich, Bell-shaped calcium-response curves of lns(l,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum, Nature, vol.351, issue.6329, pp.751-754, 1991.
DOI : 10.1038/351751a0

G. Frolenkov, Regulation of electromotility in the cochlear outer hair cell, The Journal of Physiology, vol.405, issue.1, pp.43-48, 2006.
DOI : 10.1113/jphysiol.2006.114975

Y. Mogami and S. Baba, Super-helix model: A physiological model for gravitaxis of paramecium, Advances in Space Research, vol.21, issue.8-9, pp.1291-1300, 1998.
DOI : 10.1016/S0273-1177(97)00401-8

P. Satir, K. Barkalow, and T. Hamasaki, The control of ciliary beat frequency, Trends in Cell Biology, vol.3, issue.11, pp.409-412, 1993.
DOI : 10.1016/0962-8924(93)90092-F

Y. Nakaoka, H. Tanaka, and F. Oosawa, Ca2+-dependent regulation of beat frequency of cilia in Paramecium, J Cell Sci, vol.65, pp.223-231, 1984.

S. Abdul-majeed and S. Nauli, Dopamine Receptor Type 5 in the Primary Cilia Has Dual Chemo- and Mechano-Sensory Roles, Hypertension, vol.58, issue.2, pp.325-331, 2011.
DOI : 10.1161/HYPERTENSIONAHA.111.172080

S. Abdul-majeed, B. Moloney, and S. Nauli, Mechanisms regulating cilia growth and cilia function in endothelial cells, Cellular and Molecular Life Sciences, vol.20, issue.2, 2011.
DOI : 10.1007/s00018-011-0744-0

S. Nauli, H. Haymour, W. A. Lo, S. Nauli, A. Kamkin et al., Primary Cilia are Mechanosensory Organelles in Vestibular Tissues, Mechanosensitivity and Mechanotransduction. Mechanosensitivity in Cells and Tissues, pp.317-350
DOI : 10.1007/978-90-481-9881-8_14

A. Brady and S. Tan, The Ionic Dependence of Cardiac Excitability and Contractility, The Journal of General Physiology, vol.49, issue.4, pp.781-791, 1966.
DOI : 10.1085/jgp.49.4.781

H. Einwachter, H. Haas, and R. Kern, Membrane current and contraction in frog atrial fibres, The Journal of Physiology, vol.227, issue.1, pp.141-171, 1972.
DOI : 10.1113/jphysiol.1972.sp010024

Y. Kobatake, I. Tasaki, and A. Watanabe, Phase transition in membrane with reference to nerve excitation, Adv Biophys, vol.2, pp.1-31, 1971.

R. Sah, R. Ramirez, G. Oudit, D. Gidrewicz, M. Trivieri et al., ), The Journal of Physiology, vol.74, issue.164, pp.5-18, 2003.
DOI : 10.1113/jphysiol.2002.026468

A. Braiman and Z. Priel, Efficient mucociliary transport relies on efficient regulation of ciliary beating, Respiratory Physiology & Neurobiology, vol.163, issue.1-3, pp.202-207, 2008.
DOI : 10.1016/j.resp.2008.05.010

N. Valeyev, C. Hundhausen, Y. Umezawa, N. Kotov, G. Williams et al., A Systems Model for Immune Cell Interactions Unravels the Mechanism of Inflammation in Human Skin, PLoS Computational Biology, vol.81, issue.12, p.1001024, 2010.
DOI : 10.1371/journal.pcbi.1001024.s001

P. Satir and S. Christensen, Overview of Structure and Function of Mammalian Cilia, Annual Review of Physiology, vol.69, issue.1, pp.377-400, 2007.
DOI : 10.1146/annurev.physiol.69.040705.141236

C. Hook and E. Hildebrand, Excitation of paramecium, Journal of Mathematical Biology, vol.9, issue.2, pp.197-214, 1979.
DOI : 10.1007/BF00279722