The many routes of bacterial transfer RNAs after aminoacylation.

Sylvain Blanquet (1) , Yves Mechulam (1) , Emmanuelle Schmitt (1)

1 BIOC - Laboratoire de Biochimie de l'Ecole polytechnique

Subsequent to their aminoacylation, tRNAs are subject to specific maturation and/or correction processes. Aminoacylated tRNAs ready for use in translation are then specifically channelled to the ribosomal A or P sites. Structural and biochemical studies have opened the way towards furthering our understanding of these routes to the ribosome, which involve a strict distinction between initiator and elongator tRNAs.

Domains: Biochemistry, Molecular Biology

Sylvain Blanquet, Yves Mechulam, Emmanuelle Schmitt. The many routes of bacterial transfer RNAs after aminoacylation.. Current Opinion in Structural Biology, 2000, 10 (1), pp.95-101. ⟨10.1016/S0959-440X(99)00055-X⟩. ⟨hal-00771902⟩