Oxazole Synthesis from Isocyanides

Laurent El Kaim (1) , Laurence Grimaud (1) , Pravin Patil (1)

1 DCSO - Laboratoire de synthèse organique

A new synthetic path toward oxazoles starting from isocyanides is presented. This two-step oxazole preparation involves a bromination-cyclization followed by a Suzuki cross-coupling. © Georg Thieme Verlag.

Laurent El Kaim, Laurence Grimaud, Pravin Patil. Oxazole Synthesis from Isocyanides. SYNLETT, 2012, 23 (9), pp.1361-1363. ⟨10.1055/s-0031-1290939⟩. ⟨hal-00949986⟩