Palladium-catalyzed ring opening of aminocyclopropyl Ugi adducts

Aurélie dos Santos (1) , Laurent El Kaim (1, 2) , Laurence Grimaud (1) , Romain Ramozzi (1)

1 DCSO - Laboratoire de synthèse organique
2 SOR - Synthèse Organique et Réactivité

The ring opening of aminocyclopropanes triggered by activation with an intramolecular arylpalladium(II) iodide complex is an interesting strategy for the synthesis of nitrogen heterocycles and a valuable Ugi postcondensation-type transformation. Six- and seven-membered-ring cyclic enamines may be obtained. © Georg Thieme Verlag Stuttgart * New York.

Domaines: Chimie organique

Aurélie dos Santos, Laurent El Kaim, Laurence Grimaud, Romain Ramozzi. Palladium-catalyzed ring opening of aminocyclopropyl Ugi adducts. SYNLETT, 2012, 3, pp.438-442. ⟨10.1055/s-0031-1290312⟩. ⟨hal-00949987⟩