Ugi-Smiles couplings of 4-substituted pyridine derivatives: A fast access to chloroquine analogues

Laurent El Kaim 1 Laurence Grimaud 1 Patil Pravin 1
1 DCSO - Laboratoire de synthèse organique
Abstract : 4-Hydroxy and mercapto pyridines were successfully tested in Ugi-Smiles couplings. Such multicomponent reactions applied to quinoline derivatives afford a very convenient and short synthesis of antimalarial analogues. © 2011 American Chemical Society.
Document type :
Journal articles
Complete list of metadatas
https://hal-polytechnique.archives-ouvertes.fr/hal-00949992
Contributor : Denis Roura <>
Submitted on : Tuesday, February 25, 2014 - 1:09:21 PM
Last modification on : Thursday, February 7, 2019 - 5:16:40 PM

Identifiers

Collections

CNRS | X-DCSO | X | PARISTECH | INC-CNRS | X-DEP-CHIM

Citation

Laurent El Kaim, Laurence Grimaud, Patil Pravin. Ugi-Smiles couplings of 4-substituted pyridine derivatives: A fast access to chloroquine analogues. Organic Letters, American Chemical Society, 2012, 14 (2), pp.476-478. ⟨10.1021/ol202974w⟩. ⟨hal-00949992⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

198

Contact

Informations

CCSD