An approach to α-keto vinyl carbinols

Marie-Gabrielle Braun (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

Adducts from the radical addition of xanthates to ethyl vinyl sulfide readily undergo elimination of the xanthate group upon thermolysis to give vinylic and/or allylic sulfides, depending on the structure. In the case of a-xanthyl ketones, the adducts are converted into a-keto vinyl carbinols by rearrangement of the sulfoxides derived from the vinylic and allylic sulfides. © 2011 American Chemical Society.

Domaines: Chimie organique

Marie-Gabrielle Braun, Samir Z. Zard. An approach to α-keto vinyl carbinols. Organic Letters, 2011, 13 (4), pp.776-779. ⟨10.1021/ol103044x⟩. ⟨hal-00950010⟩