Copper-catalyzed aerobic oxidative cyclization of hydrazones to pyrazolidinones

Aurélie dos Santos (1) , Laurent El Kaim (1) , Laurence Grimaud (1) , Caroline Ronsseray (1)

1 DCSO - Laboratoire de synthèse organique

N-Aryl hydrazones participate, under copper catalysis, in a [3+2] cycloaddition/aerobic oxidation cascade reaction to form pyrazolidinones. The starting hydrazones were prepared by three-component coupling of allylic amines, acyl chlorides, and aryl diazonium salts. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Aurélie dos Santos, Laurent El Kaim, Laurence Grimaud, Caroline Ronsseray. Copper-catalyzed aerobic oxidative cyclization of hydrazones to pyrazolidinones. European Journal of Organic Chemistry, 2011, 2011 (17), pp.3117-3121. ⟨10.1002/ejoc.201100261⟩. ⟨hal-00950011⟩