Enantioselective synthesis of a taxol C ring

Cong Ma 1 Stéphanie Schiltz 1 J. Prunet 2
1 DCSO - Laboratoire de synthèse organique
2 School of Chemistry
Abstract : An enantioselective synthesis of a C ring of taxol has been accomplished. The key step is an oxidative cleavage of a derivative of the Wieland-Miescher ketone. A first attempt of a Shapiro reaction modelling the coupling of the C ring with the A fragment of taxol was also successful. © 2011 Institute of Organic Chemistry and Biochemistry.
Document type :
Journal articles
Complete list of metadatas
https://hal-polytechnique.archives-ouvertes.fr/hal-00950021
Contributor : Denis Roura <>
Submitted on : Wednesday, February 26, 2014 - 9:47:14 AM
Last modification on : Thursday, February 7, 2019 - 5:14:14 PM

Identifiers

Collections

X-DCSO | X | PARISTECH | INC-CNRS | X-DEP-CHIM

Citation

Cong Ma, Stéphanie Schiltz, J. Prunet. Enantioselective synthesis of a taxol C ring. Collection of Czechoslovak Chemical Communications, Institute of Organic Chemistry & Biochemistry, 2011, 76 (12), pp.1579-1594. ⟨10.1135/cccc2011039⟩. ⟨hal-00950021⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

153

Contact

support.ccsd.cnrs.fr
hal.support@ccsd.cnrs.fr
Logo CCSD