Oxime derivatives as a-electrophiles. from a-tetralone oximes to tetracyclic frameworks

Béatrice Quiclet-Sire (1) , Nina Tölle (1) , Syeda N. Zafar (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

When subjected to the conditions of a Semmler-Wolff/Schroeter aromatization, the oximes of 4-benzyl-substituted tetralones undergo an electrophilic aromatic substitution reaction to form tetracyclic frameworks. © 2011 American Chemical Society.

Domains: Organic chemistry

Béatrice Quiclet-Sire, Nina Tölle, Syeda N. Zafar, Samir Z. Zard. Oxime derivatives as a-electrophiles. from a-tetralone oximes to tetracyclic frameworks. Organic Letters, 2011, 13 (12), pp.3266-3269. ⟨10.1021/ol2012204⟩. ⟨hal-00951231⟩