Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles

Abstract : Pyrazolidinones were prepared in a two-step sequence starting from a-hydrazonocarboxylic acids. After a four-component Ugi coupling, the resulting hydrazone was engaged in a copper triggered [3 + 2] cycloaddition/aerobic oxidation cascade. © 2011 Santos et al; licensee Beilstein-Institut.
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Aurélie dos Santos, Laurent El Kaim, Laurence Grimaud, Caroline Ronsseray. Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles. Beilstein Journal of Organic Chemistry, Beilstein-Institut, 2011, 7, pp.1310-1314. ⟨10.3762/bjoc.7.153⟩. ⟨hal-00951236⟩

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