A flexible route to 4-substituted ß-lactams

Abstract : A variety of 4-substituted ß-lactams can be readily prepared by the radical addition-transfer of 4-S-xanthyl-azetidinones to unactivated olefins. For this radical chain process to operate efficiently it is necessary to place an acyl group on the nitrogen of the azetidinone ring. © The Japan Institute of Heterocyclic Chemistry.
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Béatrice Quiclet-Sire, Samir Zard. A flexible route to 4-substituted ß-lactams. Heterocycles, The Japan Institute of Heterocyclic Chemistry, 2010, 82 (1), pp.263-271. ⟨10.3987/com-10-s(e)39⟩. ⟨hal-00951247⟩

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