A radical-based approach to hydroxytetralones from unprotected phenols

Laurent Petit (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

Xanthates derived from unprotected 2-hydroxyacetophenones undergo smooth intermolecular addition to unactivated alkenes and subsequent cyclisation to give hydroxytetralones in good yield. © The Royal Society of Chemistry 2010.

Domains: Organic chemistry

Laurent Petit, Samir Z. Zard. A radical-based approach to hydroxytetralones from unprotected phenols. Chemical Communications, 2010, 46 (28), pp.5148-5150. ⟨10.1039/c0cc00680g⟩. ⟨hal-00951248⟩