A versatile radical based approach to O-alkylated hydroxylamines and oximes

Béatrice Quiclet-Sire; Daniel Woollaston; Samir Zard

A versatile radical based approach to O-alkylated hydroxylamines and oximes

Béatrice Quiclet-Sire ¹ Daniel Woollaston ¹ Samir Zard ^{1, *}

* Corresponding author

1 DCSO - Laboratoire de synthèse organique

Abstract : O-Alkylhydroxylamines, often used for the preparation of bioconjugates, can be readily obtained by radical addition to suitable O-alkenylhydroxylamine derivatives. In the case of N-Boc-O-allylhydroxylamine, the addition is unexpectedly followed by elimination resulting in an overall allylation of the radical species. © 2008 Elsevier Ltd. All rights reserved.

Document type :

Journal articles

Domain :

Chemical Sciences / Organic chemistry

Complete list of metadatas

https://hal-polytechnique.archives-ouvertes.fr/hal-00951273
Contributor : Denis Roura <>
Submitted on : Monday, March 3, 2014 - 2:06:28 PM
Last modification on : Thursday, February 7, 2019 - 5:03:22 PM

A versatile radical based approach to O-alkylated hydroxylamines and oximes

Identifiers

Collections

Citation

Export

Metrics

179

Contact

A versatile radical based approach to O-alkylated hydroxylamines and oximes

Identifiers

Collections

Citation

Export

Share

Metrics

179

Contact