Generation and intermodular additions of pyridylmethyl radicals

Zorana Ferjancic (1) , Béatrice Quiclet-Sire (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

2-, 3-, or 4-Pyridylmethyl radicals can be made to add to nonactivated alkenes to give a variety of otherwise inaccessible pyridine derivatives. Bicyclic structures can be obtained by combining the radical addition with ionic ring-closure steps. © Georg Thieme Verlag Stuttgart.

Domaines: Chimie organique

Zorana Ferjancic, Béatrice Quiclet-Sire, Samir Z. Zard. Generation and intermodular additions of pyridylmethyl radicals. Synthesis: Journal of Synthetic Organic Chemistry, 2008, 18, pp.2996-3008. ⟨10.1055/s-2008-1067198⟩. ⟨hal-00951274⟩