Synthesis of allocolchicines using sequential ring-closing enyne metathesis - Diels - Alder reactions

François-Didier Boyer 1 Issam Hanna 2, *
* Corresponding author
1 UCB - Chimie Biologique
2 DCSO - Laboratoire de synthèse organique
Abstract : New allocolchinoids having functionality in the C ring at position C10 or C11 have been synthesized using the enyne ring-closing metathesis (RCM) reaction for construction of the seven-membered ring and a Diels-Alder-aromatization sequence for the elaboration of the aromatic ring C. © 2007 American Chemical Society.
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Submitted on : Monday, March 3, 2014 - 2:36:52 PM
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François-Didier Boyer, Issam Hanna. Synthesis of allocolchicines using sequential ring-closing enyne metathesis - Diels - Alder reactions. Organic Letters, American Chemical Society, 2007, 9 (4), pp.715-718. ⟨10.1021/ol0630548⟩. ⟨hal-00951292⟩

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