A short total synthesis of (±)-aspidospermidine

Lisa A. Sharp (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

A cascade radical cyclization starting from an amidyl radical has been used for the construction of (±)-aspidospermidine. This approach has also been developed for the preparation of a tricycle whose framework is contained in the stemona alkaloids. © 2006 American Chemical Society.

Domaines: Chimie organique

Lisa A. Sharp, Samir Z. Zard. A short total synthesis of (±)-aspidospermidine. Organic Letters, 2006, 8 (5), pp.831-834. ⟨10.1021/ol052749q⟩. ⟨hal-00951295⟩