Cyano(ethoxycarbonothioylthio)methyl benzoate: A novel one-carbon radical equivalent

Sharanjee K. Bagal (1) , Michiel de Greef (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

(Chemical Equation Presented) Cyano(ethoxycarbonothioylthio)methyl benzoate 3 has been prepared and shown to be an excellent one-carbon radical equivalent that can be applied for the introduction of an acyl unit via xanthate transfer radical addition to olefins. The corresponding adducts can be further elaborated. A rare 1,5-nitrile translocation was also observed during the study. © 2006 American Chemical Society.

Domaines: Chimie organique

Sharanjee K. Bagal, Michiel de Greef, Samir Z. Zard. Cyano(ethoxycarbonothioylthio)methyl benzoate: A novel one-carbon radical equivalent. Organic Letters, 2006, 8 (1), pp.147-150. ⟨10.1021/ol052634m⟩. ⟨hal-00951307⟩