Substituted allyl diphenylphosphine oxides as radical allylating agents

Gilles Ouvry (1) , Béatrice Quiclet-Sire (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

(Chemical Equation Presented) Radically useful: The radical addition of dithiocarbonates to branched allyl diphenylphosphine oxides can be followed by elimination of a diphenylphosphinoyl radical, thereby giving rise to allylated products (see scheme; Phth = phthalimido). Highly functionalized structures can thus be rapidly assembled under mild conditions and from cheap and readily available substrates and reagents. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

Gilles Ouvry, Béatrice Quiclet-Sire, Samir Z. Zard. Substituted allyl diphenylphosphine oxides as radical allylating agents. Angewandte Chemie International Edition, 2006, 45 (30), pp.5002-5006. ⟨10.1002/anie.200601556⟩. ⟨hal-00954781⟩