Synthesis of substituted 4-arylpiperidin-2-ones by a 6-exo-trig radical cyclization

Abstract : A series of 5-substituted-4-arylpiperidin-2-ones have been synthesized in a 4 step sequence involving a radical 6-exo-trig cyclization as the key step. © 2006 The Japan Institute of Heterocyclic Chemistry.
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Xavier Vila, Samir Zard. Synthesis of substituted 4-arylpiperidin-2-ones by a 6-exo-trig radical cyclization. Heterocycles, The Japan Institute of Heterocyclic Chemistry, 2006, 70 (1), pp.45-50. ⟨10.3987/COM-06-S(W)7⟩. ⟨hal-00954782⟩

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