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Synthesis of substituted 4-arylpiperidin-2-ones by a 6-exo-trig radical cyclization

Abstract : A series of 5-substituted-4-arylpiperidin-2-ones have been synthesized in a 4 step sequence involving a radical 6-exo-trig cyclization as the key step. © 2006 The Japan Institute of Heterocyclic Chemistry.
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https://hal-polytechnique.archives-ouvertes.fr/hal-00954782
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Submitted on : Monday, March 24, 2014 - 8:39:17 PM
Last modification on : Thursday, December 9, 2021 - 2:26:02 PM

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Xavier Vila, Samir Z. Zard. Synthesis of substituted 4-arylpiperidin-2-ones by a 6-exo-trig radical cyclization. Heterocycles, 2006, 70 (1), pp.45-50. ⟨10.3987/COM-06-S(W)7⟩. ⟨hal-00954782⟩

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