A direct approach to a-hydroxy and a-chloro trifluoromethyl derivatives

Lucie Tournier (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

S-1-Acyloxy-2,2,2-trifluoroethyl and S-1-chloro-2,2,2-trifluoroethyl dithiocarbonates add efficiently to various functionalised olefins to give the corresponding adducts via a radical chain reaction initiated by a small amount of lauroyl peroxide. S-1-Acyloxy-2,2,2-trifluoroethyl and S-1-chloro-2,2,2- trifluoroethyl dithiocarbonates add efficiently to various functionalised olefins to give the corresponding adducts via a radical chain reaction initiated by a small amount of lauroyl peroxide. © 2004 Elsevier Ltd. All rights reserved.

Lucie Tournier, Samir Z. Zard. A direct approach to a-hydroxy and a-chloro trifluoromethyl derivatives. Tetrahedron Letters, 2005, 46 (3), pp.455-459. ⟨10.1016/j.tetlet.2004.11.086⟩. ⟨hal-00954801⟩