Synthesis of substituted naphthalenes from a-tetralones generated by a xanthate radical addition-cyclisation sequence

Alejandro Cordero-Vargas (1) , Inès Pérez-Martín (1) , Béatrice Quiclet-Sire (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

A simple, highly efficient and cheap synthesis of substituted naphthalenes is reported. These aromatic compounds can be easily prepared in acidic or basic conditions from a-tetralones, obtained by a xanthate-mediated addition-cyclisation sequence.

Alejandro Cordero-Vargas, Inès Pérez-Martín, Béatrice Quiclet-Sire, Samir Z. Zard. Synthesis of substituted naphthalenes from a-tetralones generated by a xanthate radical addition-cyclisation sequence. Organic & Biomolecular Chemistry, 2004, 2, pp.3018-3025. ⟨10.1039/b411158c⟩. ⟨hal-00954817⟩