A flexible strategy for the divergent modification of pleuromutilin

Abstract : The complex antibacterial natural product, pleuromutilin, can be directly modified by the radical addition reaction of various xanthates to the unactivated terminal olefin present on C-12.
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Submitted on : Tuesday, March 18, 2014 - 8:52:24 PM
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E. Bacqué, François Pautrat, Samir Zard. A flexible strategy for the divergent modification of pleuromutilin. Chemical Communications, Royal Society of Chemistry, 2002, - (20), pp.2312-2313. ⟨10.1039/B206568A⟩. ⟨hal-00954843⟩

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