A mild exchange reaction of xanthates with bromine

Francis Barbier (1) , François Pautrat (1) , Béatrice Quiclet-Sire (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

Secondary S-alkyl-O-ethyl (or O-neopentyl) xanthates can be converted into the corresponding bromides by heating with ethyl 2-bromo-2-methylpropionate and cumyl peroxide in refluxing chlorobenzene; this transformation can be coupled to a xanthate transfer radical addition to an olefin.

Francis Barbier, François Pautrat, Béatrice Quiclet-Sire, Samir Z. Zard. A mild exchange reaction of xanthates with bromine. SYNLETT, 2002, 5, pp.811-813. ⟨10.1055/s-2002-25343⟩. ⟨hal-00954844⟩