A new tin-free source of amidyl radicals

Fabien Gagosz (1) , Cécille Moutrille (1) , Samir Z. Zard (1)

1 DCSO - Laboratoire de synthèse organique

(Matrix presented) The readily available N-(O-ethyl thiocarbonylsulfanyl)amides are powerful amidyl radical precursors that undergo 5-exo cyclization to give pyrrolidinone derivatives via a radical-chain reaction initiated by a small amount of lauroyl peroxide.

Domaines: Chimie organique

Fabien Gagosz, Cécille Moutrille, Samir Z. Zard. A new tin-free source of amidyl radicals. Organic Letters, 2002, 4 (16), pp.2707-2709. ⟨10.1021/ol026221m⟩. ⟨hal-00954848⟩