Enhancement of water suppression by radiation damping-based manipulation of residual water in Jump and Return NMR experiments

Abstract : It is shown in this Letter that amplification of radiation damping obtained by electronic feedback between consecutive transients of a Jump-Return (JR) experiment, residual in-plans water magnetization is suppressed, leading to substantial enhancement of water suppression. Application of this approach to RNA spectroscopy, where JR is particularly useful, is shown. (C) 2001 Elsevier Science B.V. All rights reserved.