Influence of copper(II) acetate on Ni/AcOH-promoted 5-endo and 5-exo radical cyclisations of trichloroacetamides

Abstract : Incorporation of Cu(OAc)2 as oxidant in Ni/AcOH-promoted 5-endo radical cyclisations of N-alkenyl-trichloroacetamides allows an interesting control of the oxidation level of the products, as illustrated by the conversion of 3 into either 4 or 5. In addition, allylic trichloroacetamides 13a-f under the same conditions underwent a 5-exo radical cyclisation-oxidation sequence leading to unsaturated hydroindolones, which represent valuable synthetic intermediates.
Type de document :
Article dans une revue
SYNLETT, Georg Thieme Verlag, 2000, pp.471-474. 〈10.1055/s-2000-6556〉
Liste complète des métadonnées

https://hal-polytechnique.archives-ouvertes.fr/hal-00954902
Contributeur : Denis Roura <>
Soumis le : mardi 11 mars 2014 - 13:34:23
Dernière modification le : jeudi 10 mai 2018 - 02:07:42

Identifiants

Collections

Citation

J. Cassayre, D. Dauge, Samir Zard. Influence of copper(II) acetate on Ni/AcOH-promoted 5-endo and 5-exo radical cyclisations of trichloroacetamides. SYNLETT, Georg Thieme Verlag, 2000, pp.471-474. 〈10.1055/s-2000-6556〉. 〈hal-00954902〉

Partager

Métriques

Consultations de la notice

161