Some new perspectives for the synthesis of organofluorine compounds

Abstract : Our research group is mostly concerned with the discovery and development of new reactions and processes that could be useful in organic synthesis. As is usually the case in scientific research, the interplay between conjecture and chance observation underlies much of our work. Unexpected events often bring a fresh lighting to the system being examined and open doors hitherto unsuspected. Misconception has thus played an important role by allowing us to uncover a number of new radical and non radical reactions of some generality involving sulfur and nitro compounds, acetylenes, oximes and related derivatives: we simply followed the logical consequences of our observations and went where the chemistry took us. In this lecture, some of the new reactions we have discovered and their application to the synthesis of a wide array of organofluorine derivatives of interest to medicinal and agrochemical chemists will be presented and discussed.
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Samir Zard. Some new perspectives for the synthesis of organofluorine compounds. Current Frontiers of Fluoroorganic Chemistry, The 230th ACS National Meeting, Aug 2005, Washington, United States. pp.FLUO 17. ⟨hal-00965881⟩

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