A convergent, unified approach to functionalized fluoro- and trifluoromethyl alkenes.

Laurent Debien (1) , Béatrice Quiclet-Sire (1) , Samir S. Zard (1)

1 DCSO - Laboratoire de synthèse organique

A modular, convergent, and operationally simple route to trifluoromethyl alkenes and vinyl fluorides involving a unique carbon-oxygen bond homolysis is reported. Highly functionalized trifluoromethyl alkenes and vinyl fluorides were obtained in good yields and good selectivity.

Domains: Organic chemistry

Laurent Debien, Béatrice Quiclet-Sire, Samir S. Zard. A convergent, unified approach to functionalized fluoro- and trifluoromethyl alkenes.. Organic Letters, 2012, 14 (19), pp.5118-21. ⟨10.1021/ol3023903⟩. ⟨hal-00967571⟩