Gold(I)-catalyzed [4+2] cycloaddition of N-(hex-5-enynyl) tert-butyloxycarbamates

Andrea Buzas (1) , Florin M. Istrate (1) , X. F Le Goff (2) , Yann Odabachian (1) , Fabien L. Gagosz (1)

1 DCSO - Laboratoire de synthèse organique
2 DCPH - Laboratoire Hétéroéléments et Coordination

A study concerning the gold(I)-catalyzed transformation of N-(hex-5-enynyl) tert-butyloxycarbamates is described. The mild conditions employed allow the moderately efficient but stereoselective synthesis of a range of bicyclic carbamates following a formal [4+2] cycloaddition process.

Domaines: Chimie organique

Andrea Buzas, Florin M. Istrate, X. F Le Goff, Yann Odabachian, Fabien L. Gagosz. Gold(I)-catalyzed [4+2] cycloaddition of N-(hex-5-enynyl) tert-butyloxycarbamates. Journal of Organometallic Chemistry, 2009, 694 (4), pp.515-519. ⟨10.1016/j.jorganchem.2008.11.004⟩. ⟨hal-00968361⟩