Facile and Efficient One-Pot Synthesis of Highly Functionalized Thieno[2,3b]thiopyran-4-ones from b-Keto e-Xanthyl Phosphonates

Abstract : Synthesis of various functionalized thieno[2,3-b]thiopyran-4-ones from readily available β-keto ε-xanthyl phosphonates has been accomplished by combining a Horner−Wadsworth−Emmons olefination with a base-induced intramolecular domino cyclization/thio-Michael addition. The use of cyclic ketones in this transformation allowed a facile access to novel spiro-type thieno[2,3-b]thiopyran structures.
Type de document :
Article dans une revue
Organic Letters, American Chemical Society, 2008, 10 (13), pp.2861-2864. 〈10.1021/ol801033〉
Liste complète des métadonnées

https://hal-polytechnique.archives-ouvertes.fr/hal-00968362
Contributeur : Denis Roura <>
Soumis le : lundi 31 mars 2014 - 21:22:07
Dernière modification le : jeudi 10 mai 2018 - 02:07:44

Identifiants

Collections

Citation

Matthieu Corbet, Samir Zard. Facile and Efficient One-Pot Synthesis of Highly Functionalized Thieno[2,3b]thiopyran-4-ones from b-Keto e-Xanthyl Phosphonates. Organic Letters, American Chemical Society, 2008, 10 (13), pp.2861-2864. 〈10.1021/ol801033〉. 〈hal-00968362〉

Partager

Métriques

Consultations de la notice

124