α-Scission of sulfonyl radicals: a versatile process for organic synthesis

Frédéric Bertrand (1) , Frédéric Le Guyader (1) , Lucia Liguori (1) , Gilles Ouvry (2) , Béatrice Quiclet-Sire (1, 2) , Stéphanie Seguin (1) , Samir Z. Zard (1, 2)

1 ICSN - Institut de Chimie des Substances Naturelles
2 DCSO - Laboratoire de synthèse organique

The reversible addition of aliphatic radicals to sulphur dioxide can be exploited to design a variety of tin-free chain reactions. This brief review summarises some of the possibilities, namely radical allylation, vinylation, alkynylation, and azidation of various substrates.

Frédéric Bertrand, Frédéric Le Guyader, Lucia Liguori, Gilles Ouvry, Béatrice Quiclet-Sire, et al.. α-Scission of sulfonyl radicals: a versatile process for organic synthesis. Comptes Rendus de l'Academie des Sciences Serie II, 2001, 4 (7), pp.547-555. ⟨10.1016/S1387-1609(01)01270-1⟩. ⟨hal-00969330⟩