Comparative Study of the Folding/Unfolding Dynamics of Poly(glutamic acid) in Light and Heavy Water

Lucille Mendonça 1 Andreas Steinbacher 1 Raphaël Bouganne 1 François Hache 1, *
* Auteur correspondant
1 LOB - Laboratoire d'optique et biosciences
Abstract : The folding/unfolding equilibrium is investigated in poly(glutamic acid) (PGA) by two complementary sets of experiments: temperature-dependent steady-state circular dichroism spectra on the one hand and time-resolved circular dichroism measurements coupled with a T-jump experiment on the other hand. The experiments are performed for PGA dissolved in water for various pH values, as well as in heavy water. The kinetic and thermodynamic parameters extracted from these measurements are shown to be markedly different between light and heavy water, which is assigned to the difference in hydrogen bond energies in both solvents.
Type de document :
Article dans une revue
Journal of Physical Chemistry B, American Chemical Society, 2014, 118 (20), pp.5350-5356. 〈10.1021/jp501282z〉
Liste complète des métadonnées
https://hal-polytechnique.archives-ouvertes.fr/hal-01015311
Contributeur : Denis Roura <>
Soumis le : jeudi 26 juin 2014 - 11:15:57
Dernière modification le : jeudi 7 février 2019 - 16:03:57

Identifiants

Collections

X | X-LOB | PARISTECH | X-DEP-BIO

Citation

Lucille Mendonça, Andreas Steinbacher, Raphaël Bouganne, François Hache. Comparative Study of the Folding/Unfolding Dynamics of Poly(glutamic acid) in Light and Heavy Water. Journal of Physical Chemistry B, American Chemical Society, 2014, 118 (20), pp.5350-5356. 〈10.1021/jp501282z〉. 〈hal-01015311〉

Exporter

BibTeX TEI DC DCterms EndNote

Partager

Métriques

Consultations de la notice

151

Contact

support.ccsd.cnrs.fr
hal.support@ccsd.cnrs.fr
Logo CCSD