Abstract : Unprecedented examples of a synthetically useful radical ring closure onto a pyrimidine nitrogen leading to novel, highly functionalized bi- and tricyclic pyrimidone structures are reported. An unexpected hydrogen atom translocation prior to the cyclization step was observed in some cases.
Ling Qin, Zhibo Liu, Samir Zard. Carbon Radical Attack on a Pyrimidine Nitrogen. An Unusual Entry into Polycyclic Aminopyrimidones. Organic Letters, American Chemical Society, 2014, 16 (11), pp.2966-2969. ⟨10.1021/ol501104h⟩. ⟨hal-01017929⟩
