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Aspiration of biological viscoelastic drops
Abstract : Spherical cellular aggregates are in vitro systems to study the physical and biophysical properties of tissues. We present a novel approach to characterize the mechanical properties of cellular aggregates using a micropipette aspiration technique. We observe an aspiration in two distinct regimes: a fast elastic deformation followed by a viscous flow. We develop a model based on this viscoelastic behavior to deduce the surface tension, viscosity, and elastic modulus. A major result is the increase of the surface tension with the applied force, interpreted as an effect of cellular mechanosensing. © 2010 The American Physical Society.
Cited literature [23 references]
https://hal-polytechnique.archives-ouvertes.fr/hal-01020626
Contributor : Denis Roura Connect in order to contact the contributor
Submitted on : Tuesday, July 8, 2014 - 12:50:33 PM
Last modification on : Tuesday, December 7, 2021 - 10:58:03 AM
Long-term archiving on: : Wednesday, October 8, 2014 - 1:25:19 PM
Contributor : Denis Roura Connect in order to contact the contributor
Submitted on : Tuesday, July 8, 2014 - 12:50:33 PM
Last modification on : Tuesday, December 7, 2021 - 10:58:03 AM
Long-term archiving on: : Wednesday, October 8, 2014 - 1:25:19 PM
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APhysRevLett.104.218101_1_.pdf
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