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Dynamics of Arterial Wall Transport for Small Hydrophobic Drugs

Abstract : Drugs used in drug-eluting stents (DES) to inhibit proliferation of smooth muscle cells (SMCs) also limit re-endothelialization at the site of stent implantation [1]. Thus, treated patients face an increased risk of late-stent thrombosis. Avoiding this adverse side effect represents one of the major challenges in the design of next-generation DES.
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Franz Bozsak, Jean-Marc Chomaz, Abdul I. Barakat. Dynamics of Arterial Wall Transport for Small Hydrophobic Drugs. 2012 Summer Bioengineering Conference, Jun 2012, Fajardo, Puerto Rico, United States. pp.565-566, ⟨10.1115/SBC2012-80541⟩. ⟨hal-01025967⟩



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