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Journal Articles European Journal of Organic Chemistry Year : 2014

Pyrrolidinone and Piperidinone Isocyanides from Isocyano Esters

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Abstract

The alkylation of isocyano esters with 1,2- and 1,3-dibromoalkanes affords bromo isocyanides. Under treatment with various amines the latter form new isocyano-substituted lactams, which can be further used in Passerini or Ugi reactions.

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hal-01065722 , version 1 (18-09-2014)

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Naïm Ait Sidhoum, Aurélie dos Santos, Laurent El Kaim, Laetitia Legras. Pyrrolidinone and Piperidinone Isocyanides from Isocyano Esters. European Journal of Organic Chemistry, 2014, 2014 (23), pp.4949-4952. ⟨10.1002/ejoc.201402572⟩. ⟨hal-01065722⟩
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