Stabilization of radicals by imides. A modular stereoselective approach to protected functional 1,2-diamines.

Abstract : Radical addition of various xanthates to N,N'-diacylimidazol-2-one occurs readily to give protected 1,2-diamines. The imide group stabilizes the adduct radical sufficiently to enable a second addition to unactivated alkenes. In some cases, the addition product could be converted into an indoline, a tetralone, or further added to an indole. Regioselective removal of one acyl group could also be accomplished.
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Article dans une revue
Letters in Organic Chemistry, Bentham Science Publishers, 2014, 16 (20), pp.5386-5389
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Soumis le : lundi 29 décembre 2014 - 18:07:56
Dernière modification le : jeudi 11 janvier 2018 - 06:18:30

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  • HAL Id : hal-01098821, version 1
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Songzhe Han, Samir Z Zard. Stabilization of radicals by imides. A modular stereoselective approach to protected functional 1,2-diamines.. Letters in Organic Chemistry, Bentham Science Publishers, 2014, 16 (20), pp.5386-5389. 〈hal-01098821〉

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