Passerini/Tsuji-Trost strategies towards achieving lactams and cyclopentane derivatives. - Archive ouverte HAL Access content directly
Journal Articles Chemical Communications Year : 2015

Passerini/Tsuji-Trost strategies towards achieving lactams and cyclopentane derivatives.

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Abstract

The Passerini reaction of α,β-unsaturated aldehydes affords suitable substrates for the Tsuji-Trost reaction with various carbon based-nucleophiles. The resulting α,β-unsaturated amides may be cyclized to lactams or converted into cyclopentane derivatives if bis-nucleophiles are used in the Tsuji-Trost step.
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Dates and versions

hal-01152233 , version 1 (15-05-2015)

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Marie Cordier, Aurélie dos Santos, Laurent El Kaim, Noisette Narboni. Passerini/Tsuji-Trost strategies towards achieving lactams and cyclopentane derivatives.. Chemical Communications, 2015, 51 (29), pp.6411-4. ⟨10.1039/C5CC00584A⟩. ⟨hal-01152233⟩
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