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Journal articles
Elastocapillary Instability in Mitochondrial Fission
Abstract : Mitochondria are dynamic cell organelles that constantly undergo fission and fusion events. These dynamical processes, which tightly regulate mitochondrial morphology, are essential for cell physiology. Here we propose an elastocapillary mechanical instability as a mechanism for mitochondrial fission. We experimentally induce mitochondrial fission by rupturing the cell's plasma membrane. We present a stability analysis that successfully explains the observed fission wavelength and the role of mitochondrial morphology in the occurrence of fission events. Our results show that the laws of fluid mechanics can describe mitochondrial morphology and dynamics.
Cited literature [20 references]
https://hal-polytechnique.archives-ouvertes.fr/hal-01207379
Contributor : Denis Roura Connect in order to contact the contributor
Submitted on : Wednesday, September 30, 2015 - 4:47:05 PM
Last modification on : Thursday, December 17, 2020 - 11:42:05 AM
Long-term archiving on: : Thursday, December 31, 2015 - 10:42:33 AM
Contributor : Denis Roura Connect in order to contact the contributor
Submitted on : Wednesday, September 30, 2015 - 4:47:05 PM
Last modification on : Thursday, December 17, 2020 - 11:42:05 AM
Long-term archiving on: : Thursday, December 31, 2015 - 10:42:33 AM
File
PhysRevLett.115.088102.pdf
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