Skip to Main content Skip to Navigation
Journal articles

Elastocapillary Instability in Mitochondrial Fission

Abstract : Mitochondria are dynamic cell organelles that constantly undergo fission and fusion events. These dynamical processes, which tightly regulate mitochondrial morphology, are essential for cell physiology. Here we propose an elastocapillary mechanical instability as a mechanism for mitochondrial fission. We experimentally induce mitochondrial fission by rupturing the cell's plasma membrane. We present a stability analysis that successfully explains the observed fission wavelength and the role of mitochondrial morphology in the occurrence of fission events. Our results show that the laws of fluid mechanics can describe mitochondrial morphology and dynamics.
Document type :
Journal articles
Complete list of metadata

Cited literature [20 references]  Display  Hide  Download
Contributor : Denis Roura Connect in order to contact the contributor
Submitted on : Wednesday, September 30, 2015 - 4:47:05 PM
Last modification on : Tuesday, September 13, 2022 - 12:46:07 PM
Long-term archiving on: : Thursday, December 31, 2015 - 10:42:33 AM


Publisher files allowed on an open archive



David Gonzalez-Rodriguez, Sébastien Sart, Avin Babataheri, David Tareste, Abdul I. Barakat, et al.. Elastocapillary Instability in Mitochondrial Fission. Physical Review Letters, American Physical Society, 2015, 115 (8), pp.088102. ⟨10.1103/PhysRevLett.115.088102⟩. ⟨hal-01207379⟩



Record views


Files downloads