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Article Dans Une Revue Physical Review Letters Année : 2015

Elastocapillary Instability in Mitochondrial Fission

Résumé

Mitochondria are dynamic cell organelles that constantly undergo fission and fusion events. These dynamical processes, which tightly regulate mitochondrial morphology, are essential for cell physiology. Here we propose an elastocapillary mechanical instability as a mechanism for mitochondrial fission. We experimentally induce mitochondrial fission by rupturing the cell's plasma membrane. We present a stability analysis that successfully explains the observed fission wavelength and the role of mitochondrial morphology in the occurrence of fission events. Our results show that the laws of fluid mechanics can describe mitochondrial morphology and dynamics.
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Dates et versions

hal-01207379 , version 1 (30-09-2015)

Identifiants

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David Gonzalez-Rodriguez, Sébastien Sart, Avin Babataheri, David Tareste, Abdul I. Barakat, et al.. Elastocapillary Instability in Mitochondrial Fission. Physical Review Letters, 2015, 115 (8), pp.088102. ⟨10.1103/PhysRevLett.115.088102⟩. ⟨hal-01207379⟩
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