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Poster communications

ROS Detection and Quantification with Lanthanide-Based Nanosensors

Abstract : Reactive oxygen species (ROS), in particular hydrogen peroxide (H2O2), are produced as secondary cellular messengers involved in a variety of signaling pathways. Detecting ROS concentration in cells and in living organisms is particularly important because ROS oxidative stress plays a complex role in multiple pathologies: inflammatory processes, neurodegenerative diseases, and cancer. We first report on an europium-based H2O2 sensor (Y0.6Eu0.4VO4) that shows red, oxidant-dependant, reversible luminescence modulation used in cells in culture.
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Poster communications
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Contributor : Denis Roura Connect in order to contact the contributor
Submitted on : Thursday, December 3, 2015 - 1:57:32 PM
Last modification on : Wednesday, October 27, 2021 - 2:15:23 PM

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Mouna Abdesselem, Thierry Gacoin, Jean-Pierre Boilot, Pierre-Louis Tharaux, Antigoni Alexandrou, et al.. ROS Detection and Quantification with Lanthanide-Based Nanosensors. 59th Annual Meeting of the Biophysical-Society, Feb 2015, Baltimore, United States. Biophysical Journal, 108 (2), pp.483a, 2015, ⟨10.1016/j.bpj.2014.11.2640⟩. ⟨hal-01237532⟩



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