A Nonoxidative Passerini Pathway to α-Ketoamides

Abdelbari Ben Abdessalem (1, 2) , Raoudha Abderrahim (2) , Laurent El Kaim (3, 1)

1 DCSO - Laboratoire de synthèse organique
2 Université de Carthage - University of Carthage
3 ENSTA Paris - École Nationale Supérieure de Techniques Avancées

The Passerini adducts of cinnamaldehyde derivatives may be efficiently converted into alpha-ketoamides when heated with a base under microwave conditions.

Domains: Chemical Sciences; Organic chemistry

Abdelbari Ben Abdessalem, Raoudha Abderrahim, Laurent El Kaim. A Nonoxidative Passerini Pathway to α-Ketoamides. SYNLETT, 2015, 26 (18), pp.2537-2540. ⟨10.1055/s-0035-1560632⟩. ⟨hal-01245816⟩