Computational Fluid Dynamic Simulations of Maternal Circulation: Wall Shear Stress in the Human Placenta and Its Biological Implications

Abstract : In the human placenta the maternal blood circulates in the intervillous space (IVS). The syncytiotrophoblast (STB) is in direct contact with maternal blood. The wall shear stress (WSS) exerted by the maternal blood flow on the STB has not been evaluated. Our objective was to determine the physiological WSS exerted on the surface of the STB during the third trimester of pregnancy.
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E. Lecarpentier, M. Bhatt, G. Bertin, B. Deloison, L. Salomon, et al.. Computational Fluid Dynamic Simulations of Maternal Circulation: Wall Shear Stress in the Human Placenta and Its Biological Implications. PLoS ONE, Public Library of Science, 2016, 11 (1), pp.e0147262. ⟨10.1371/journal.pone.0147262⟩. ⟨hal-01311196⟩

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