A Convergent Synthesis of Enantiopure Open-Chain, Cyclic, and Fluorinated α-Amino Acids

Abstract : A radical based synthesis of a broad variety of protected enantiopure alpha-amino acids, including fluorinated derivatives, is described. The radical addition furnishes naturally latent mercapto-a-amino acids ideally equipped for native chemical ligation.
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Article dans une revue
Organic Letters, American Chemical Society, 2016, 18 (8), pp.1888-1891. 〈10.1021/acs.orglett.6b00656〉
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Soumis le : lundi 30 mai 2016 - 13:08:40
Dernière modification le : jeudi 10 mai 2018 - 02:07:41

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Shi-Guang Li, Fernando Portela-Cubillo, Samir Z. Zard. A Convergent Synthesis of Enantiopure Open-Chain, Cyclic, and Fluorinated α-Amino Acids. Organic Letters, American Chemical Society, 2016, 18 (8), pp.1888-1891. 〈10.1021/acs.orglett.6b00656〉. 〈hal-01323304〉

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