Service interruption on Monday 11 July from 12:30 to 13:00: all the sites of the CCSD (HAL, EpiSciences, SciencesConf, AureHAL) will be inaccessible (network hardware connection).
Skip to Main content Skip to Navigation
Conference papers

Elastocapillary Instability in Mitochondrial Fission

Abstract : Mitochondria are dynamic cell organelles that constantly undergo fission and fusion events. These dynamical processes, which tightly regulate mitochondrial morphology, are essential for cell physiology. We propose an elastocapillary mechanical instability as a mechanism for mitochondrial fission [Gonzalez-Rodriguez et al., Phys. Rev. Lett. 115, 088102 (2015)]. We experimentally induce mitochondrial fission by rupturing the cell's plasma membrane. We present a stability analysis that successfully explains the observed fission wavelength and the role of mitochondrial morphology in the occurrence of fission events. Our results show that the laws of fluid mechanics can describe mitochondrial morphology and dynamics. © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.
Document type :
Conference papers
Complete list of metadata
Contributor : Denis Roura Connect in order to contact the contributor
Submitted on : Wednesday, June 1, 2016 - 3:42:34 PM
Last modification on : Thursday, December 17, 2020 - 11:42:05 AM

Links full text



David Gonzalez-Rodriguez, Sébastien Sart, Avin Babataheri, David Tareste, Abdul I. Barakat, et al.. Elastocapillary Instability in Mitochondrial Fission. 60th Annual Meeting of the Biophysical-Society, Biophysical-Society, Feb 2016, Los Angeles, United States. pp.472a, ⟨10.1016/j.bpj.2015.11.2527⟩. ⟨hal-01324881⟩



Record views