Passerini/Tsuji-Trost Strategy towards Pyrrole Derivatives

Abstract : The Passerini reaction of α,β‐unsaturated aldehydes affords suitable substrates for a Tsuji–Trost reaction with NH‐enamines. The latter behave as a 1,3‐bisnucleophile, which leads to the formation of pyrrole derivatives with five points of diversity through a Tsuji–Trost/Michael addition/aromatization cascade.
Document type :
Journal articles
Complete list of metadatas

https://hal-polytechnique.archives-ouvertes.fr/hal-02094146
Contributor : Aurélien Arnoux <>
Submitted on : Tuesday, April 9, 2019 - 2:49:32 PM
Last modification on : Wednesday, July 3, 2019 - 10:48:05 AM

Identifiers

Citation

Noisette Narboni, Laurent El Kaim. Passerini/Tsuji-Trost Strategy towards Pyrrole Derivatives. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2017, 2017 (29), pp.4242-4246. ⟨10.1002/ejoc.201700653⟩. ⟨hal-02094146⟩

Share

Metrics

Record views

25