Cobalt-Catalyzed Electrophilic Amination of Arylzincs with N-Chloroamines

Xin Qian (1) , Zailu Yu (1) , Audrey Auffrant (1) , C. Gosmini (1)

1 DCPH - Laboratoire Hétéroéléments et Coordination

An efficient cobalt-catalyzed electrophilic amination of arylzinc reagents has been achieved. A variety of functionalized arylzincs and N-chloroamines were coupled under mild conditions (see scheme). Both secondary and tertiary arylamines were obtained in moderate to excellent yields.

Keywords: amination; anilines; C[BOND]N coupling; cobalt; zinc

Domains: Chemical Sciences; Coordination chemistry

Xin Qian, Zailu Yu, Audrey Auffrant, C. Gosmini. Cobalt-Catalyzed Electrophilic Amination of Arylzincs with N-Chloroamines. Chemistry - A European Journal, 2013, 19 (20), pp.6225-6229. ⟨10.1002/chem.201300229⟩. ⟨hal-00906334⟩