A flexible, convergent route to azaoxindoles, azaindolines, azaindoles, and tetrahydroazaquinolones

E. Bacqué (1) , Myriem El Qacémi (2, 3) , Samir Z. Zard (3)

1 Sanofi-Aventis [Toulouse]
2 Syngenta Crop Protection AG
3 DCSO - Laboratoire de synthèse organique

A variety of azaoxindoles, azaindolines, azaindoles, and tetrahydroazaquinolones can be readily prepared by cyclisation onto pyridine rings of radicals derived from xanthates. The xanthate precursors may themselves be produced by intermolecular radical addition-transfer to allylamino- or butenoylamide side-chains. © 2012 The Japan Institute of Heterocyclic Chemistry.

Domains: Chemical Sciences; Organic chemistry

E. Bacqué, Myriem El Qacémi, Samir Z. Zard. A flexible, convergent route to azaoxindoles, azaindolines, azaindoles, and tetrahydroazaquinolones. Heterocycles, 2011, 84 (1), pp.291-299. ⟨10.3987/com-11-s(p)24⟩. ⟨hal-00950005⟩